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Prof. Dr. Mustafa Özdoğan · Medical Oncologist

Obesity in Adolescence Increases Pancreatic Cancer Risk 4-Fold

Obesity in Adolescence Increases Pancreatic Cancer Risk 4-Fold
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Pancreatic cancer, ranks 6th among causes of cancer-related death worldwide. Obesity and pancreatic cancer have a well-established relationship, but how obesity in adolescence affects pancreatic cancer risk had not previously been demonstrated. In November 2018, Cancer published a study finding that adolescent obesity increases pancreatic cancer risk 4-fold. Overweight adolescents who were not obese were also reported to have a certain increase in pancreatic cancer risk.

The research was conducted at Tel Aviv University in Israel. Among those aged 16-18, 1.087.358 Jewish men and 707.212 Jewish women underwent physical examinations between 1967-2002. After 23.3 years of follow-up, 551 (423 men and 128 women) were newly diagnosed with pancreatic cancer.

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According to the analysis results;

  • Compared with normal weight, obese adolescent boys had a 3.67-fold higher risk of pancreatic cancer. In women, a 4.07-fold higher cancer risk was reported.
  • High-normal body mass index in men was associated with a 49 percent increase in pancreatic cancer risk; having a high body mass index without obesity increased pancreatic cancer risk by 97 percent.

So What Does This Study Mean for Us?

  • Obesity and excess weight during adolescence were found to substantially increase pancreatic cancer risk. This is one of the studies confirming obesity as an important cause of cancer.

Related Topic:

  • What Are the Causes of Cancer - Briefly?
  • It must be emphasized that obesity is increasing particularly among adolescents. Implementing programs to guide adolescents toward healthy living is very important.
  • Obesity-related systemic inflammationhas been reported in earlier studies as a potential trigger of cancer. New scientific evidence concerning cancer and obesity emerges every day.
  • How Obesity Prevents the Immune System from Fighting Cancer Has Been Discovered.

In the video below, obesity is shown to have increased over the past 40 years by more than 2-fold. Obesity and excess weight appear likely to become the leading cause of death worldwide in the future.

Sources

Zohar Levi MD ve ark.
Adolescent overweight and obesity and the risk for pancreatic cancer among men and women: a nationwide study of 1.79 million Israeli adolescents.
Cancer, 12 November 2018
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