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What Are Biliary Stents and PTK Drains for Bile Duct Obstruction?

What Are Biliary Stents and PTK Drains for Bile Duct Obstruction?
In this article

Bile duct obstruction is a common, serious problem in cancers of the pancreatic head, biliary tract and liver. It can also occur because of gallstones . Biliary stents used to relieve obstruction can greatly improve quality of life, but what they are and how they work often seems mysterious. This article explains step by step what a biliary stent is, what bile duct obstruction means, how a stent is placed and what happens afterward, making the process easier to understand.

A simplified anatomical illustration of the biliary tract below will help explain:

Extrahepatic bile duct anatomy 2

What Is a Biliary Stent?

A biliary stent is a small tube placed in the bile ducts within the liver. It opens a blocked duct to allow bile to flow, relieving obstruction-related problems such as elevated bilirubin and jaundice .

Liver cancer, bile duct cancer and pancreatic head cancer can obstruct the bile duct. This may cause the accumulation of the yellowish pigment bilirubin, also known as bile, a digestive fluid produced by the liver, leading to jaundice. A biliary stent can help patients by opening the obstruction and relieving jaundice.

What Is PTK? Is It the Same as a Biliary Stent?

A percutaneous transhepatic catheter (PTK) is placed directly into a bile duct through an external approach to the liver, opening blocked ducts and directing accumulated bile outside the body. An interventional radiologist usually performs this under ultrasound (USG) guidance. A PTK drain is generally preferred when endoscopic intervention is impossible, to relieve obstruction-related symptoms.

Biliary stenting and percutaneous transhepatic drainage/catheterization (PTD or PTK) are different interventional procedures with similar aims. Both treat blocked or narrowed bile ducts, but their methods and details differ.

  1. Biliary Stent: Placement usually involves endoscopic retrograde cholangiopancreatography (ERCP). The stent is inserted orally (through the mouth) with an endoscope. This flexible tube is positioned in the bile duct to bypass the blockage and allow bile to flow.
  2. Percutaneous Transhepatic Drainage (PTD or PTK): A thin tube (catheter) is inserted through the skin into the upper part of the liver. It opens blocked bile ducts and directs accumulated bile outside the body. PTK is usually preferred when biliary stenting is not possible.

Both procedures have advantages, risks and complications. The choice depends on the patient's condition, overall health and other factors. If such a procedure is recommended, discussing all options and potential risks with a healthcare professional is important.

Both methods are illustrated simply below:

What are biliary stents and PTK percutaneous biliary catheters? Differences in bile duct obstruction

Bile Duct Obstruction

The bile duct transports bilirubin, also known as bile, produced in the liver. Bilirubin is an important body fluid that helps break down fats during digestion and facilitates their absorption in the intestines.

Obstruction usually results from small, solid deposits called gallstones accumulating in the duct. Other possible causes include:

  • Liver dysfunction
  • A tumor pressing on the pancreas or bile duct
  • Liver cancer

Obstruction generally causes:

  • Severe abdominal pain
  • Nausea
  • Vomiting
  • Jaundice (yellowing of skin and the whites of the eyes)
  • Weight loss

Bilirubin can accumulate in the blood and cause jaundice, the yellowing of skin and mucous membranes.

When an obstructed duct causes jaundice, a biliary stent may help. It opens the blockage and may relieve jaundice within 1-2 weeks of placement.

Placing a stent as soon as possible can reduce jaundice severity. The method may, however, be unsuitable in some circumstances, such as advanced liver cancer.

Total Bilirubin Should Not Be High for Cancer Treatment

Total bilirubin measures the amount of bilirubin in the blood. Bilirubin is a waste product produced as the liver breaks down red blood cells, usually excreted in bile. A blocked duct or impaired liver processing can raise bilirubin levels in blood and tissues, causing jaundice and yellow skin and eyes.

Blood total bilirubin should generally range from 0.1 to 1.2 milligrams per deciliter (mg/dL). Certain cancers or treatments, particularly involving the biliary tract or liver, can raise it above normal.

For patients undergoing cancer treatment, the aim is generally total bilirubin below 5 mg/dL. This is considered an indicator of treatment effectiveness and safety as well as overall health. Above this target, potential risks may increase, particularly for therapies affecting liver function. A level below 5 mg/dL is therefore important in treatment decisions.

This highlights the role of biliary stents. Opening the duct restores bile flow and helps lower bilirubin. By reducing levels quickly and effectively, the procedure enables cancer treatment to begin and proceed as effectively as possible. Stenting may therefore be crucial for cancer patients with high bilirubin.

The Biliary Stent Procedure

The procedure varies according to factors such as whether the stent is plastic or metal, where it is placed and how long it will remain.

What Should You Expect?

Before Biliary Stent Placement

The following considerations generally aim to minimize anesthesia and complication risks:

  1. Allergies: Some people may react to materials or medications used, causing an unexpected reaction during or after anesthesia.
  2. Medicines and Supplements: Some medicines and supplements may increase bleeding risk during or after the procedure or cause other complications.
  3. Smoking and Food Intake: Eating, drinking or smoking 8 hours before the procedure may increase the risk of stomach contents entering the lungs (aspiration) during general anesthesia, a potentially serious complication.
  4. Chewing Gum: Chewing gum stimulates stomach acid secretion, so the same reasons for restrictions on eating and drinking also apply to gum.
During the Procedure

Biliary stent placement, performed by interventional radiologists or gastroenterologists, is an endoscopic retrograde cholangiopancreatography (ERCP) procedure.

  1. The specialist passes a flexible, illuminated endoscope with a small camera through the mouth, down the esophagus, beyond the stomach and into the duodenum, the uppermost small intestine. This reveals the opening in the duodenal wall where bile normally enters the digestive tract.
  2. A wire and catheter are gently passed through this opening into the main bile duct.
  3. The stent slides along the wire into the duct, where the specialist positions it to bypass the obstruction. It provides an open path for bile to drain from the liver.
  4. Imaging such as X-rays or fluoroscopy may confirm correct placement.

In some cases, biliary dilation is also performed, using a balloon to widen part of the duct and relieve the blockage.

After Biliary Stent Placement

The patient may remain in hospital for monitoring and need several days of bed rest while recovering.

Specialists monitor vital signs, including oxygen level, blood pressure, pulse and temperature, until they are satisfied the patient has fully recovered.

After ERCP, patients may experience:

  • A sore throat for 1-2 days
  • Difficulty swallowing
  • Bloating
  • Nausea

Patients can resume their normal diet once swallowing is no longer difficult. Continued rest is recommended after discharge.

Do Biliary Stents or PTK Drains Need Regular Replacement?

Stents used for bile duct obstruction may need replacement at intervals determined by the patient's general condition, disease severity and stent type.

Stents are generally plastic or metal. Plastic stents, particularly in malignant (cancerous) disease, are usually recommended for replacement every 3-6 months because obstruction may recur, although the interval can be shorter. Exact replacement timing in benign disease is unclear, but one study suggests a plastic stent may remain longer and be replaced after 6 months.

Biliary stents or percutaneous transhepatic catheters (PTK) for cancer-related narrowing generally maintain bile flow when surgery is impossible. Replacement timing then depends on overall health, cancer stage and other factors.

Biliary Stenting in Summary

A biliary stent is a tube used to open blocked bile ducts in liver cancer patients. Restoring bile flow relieves jaundice. Obstruction generally results from gallstones or tumors.

Using a biliary stent requires extensive knowledge and experience. Success depends closely on teamwork, access to accurate information and appropriate use of that information. These explanations and procedures may serve as a resource for people seeking to understand biliary stents.

Biliary stenting can play a critical role in managing bile duct obstruction. In cancer patients, it relieves symptoms and facilitates treatment. Lowering total bilirubin can also substantially improve quality of life. Like every medical procedure, however, it carries risks and complications, requiring close medical supervision before and afterward.

Sources

1. Moy BT, Birk JW. An Update to Hepatobiliary Stents. J Clin Transl Hepatol. 2015 Mar;3(1):67-77. doi: 10.14218/JCTH.2015.00040. Epub 2015 Mar 15. PMID: 26357636; PMCID: PMC4542081.

2. O'Brien S, Bhutiani N, Egger ME, Brown AN, Weaver KH, Kline D, Kelly LR, Scoggins CR, Martin RCG 2nd, Vitale GC. Comparing the efficacy of initial percutaneous transhepatic biliary drainage and endoscopic retrograde cholangiopancreatography with stenting for relief of biliary obstruction in unresectable cholangiocarcinoma. Surg Endosc. 2020 Mar;34(3):1186-1190. doi: 10.1007/s00464-019-06871-2. Epub 2019 May 28. PMID: 31139984.

3. Rees J, Mytton J, Evison F, Mangat KS, Patel P, Trudgill N. The outcomes of biliary drainage by percutaneous transhepatic cholangiography for the palliation of malignant biliary obstruction in England between 2001 and 2014: a retrospective cohort study. BMJ Open. 2020 Jan 23;10(1):e033576. doi: 10.1136/bmjopen-2019-033576. PMID: 31980509; PMCID: PMC7045186.
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